{"id":12274,"date":"2018-10-19T08:59:03","date_gmt":"2018-10-19T14:59:03","guid":{"rendered":"http:\/\/otech.uaeh.edu.mx\/noti\/?p=12274"},"modified":"2018-10-19T09:02:41","modified_gmt":"2018-10-19T15:02:41","slug":"investigadores-curan-infecciones-resistentes-a-los-medicamentos-sin-antibioticos","status":"publish","type":"post","link":"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/investigadores-curan-infecciones-resistentes-a-los-medicamentos-sin-antibioticos\/","title":{"rendered":"Investigadores curan infecciones resistentes a los medicamentos sin antibi\u00f3ticos"},"content":{"rendered":"<p>Seg\u00fan un estudio, publicado en Scientific Reports, las infecciones en humanos podr\u00edan curarse de la misma manera en que se han logrado curar en ratones: sin usar antibi\u00f3ticos.<!--more--><\/p>\n<p>En lugar de matar las bacterias causantes con antibi\u00f3ticos, los investigadores trataron ratones infectados con mol\u00e9culas que bloquean la formaci\u00f3n de toxinas en las bacterias.<\/p>\n<p><strong>Sepsis<\/strong><\/p>\n<p>El tratamiento de ratones con las mol\u00e9culas terap\u00e9uticas cur\u00f3 eficazmente las infecciones causadas por Staphylococcus aureus resistente a la meticilina (SARM). S. aureus es conocido por su capacidad para superar incluso los antibi\u00f3ticos m\u00e1s potentes. Su arsenal de resistencia es amplio, limitando las opciones terap\u00e9uticas para tratar infecciones.<\/p>\n<p>Las mol\u00e9culas peque\u00f1as fueron tan efectivas para promover la supervivencia como los antibi\u00f3ticos que se usan actualmente para tratar las infecciones por S. aureus. Las mol\u00e9culas tambi\u00e9n parecen dar un impulso a los antibi\u00f3ticos.<\/p>\n<p>Los ratones s\u00e9pticos tratados con una combinaci\u00f3n de mol\u00e9culas peque\u00f1as y antibi\u00f3ticos ten\u00edan diez veces menos bacterias en el torrente sangu\u00edneo que los ratones tratados con antibi\u00f3ticos solos.<\/p>\n<p>\u201cPara los pacientes relativamente sanos, como los atletas que sufren una infecci\u00f3n por SARM, estas mol\u00e9culas pueden ser suficientes para eliminar una infecci\u00f3n \u201c, se\u00f1al\u00f3 Menachem Shoham, profesor asociado de bioqu\u00edmica en la Escuela de Medicina de la Universidad Case Western Reserve y autor principal del estudio:<\/p>\n<p>Para pacientes inmunocomprometidos, la terapia de combinaci\u00f3n con las mol\u00e9culas y un antibi\u00f3tico de dosis baja puede ser suficiente. Con el apoyo de las mol\u00e9culas peque\u00f1as, los antibi\u00f3ticos previamente obsoletos podr\u00edan volver a ingresar a la cl\u00ednica.<\/p>\n<p>Los antibi\u00f3ticos matan a la mayor\u00eda de las bacterias, pero sobrevive una peque\u00f1a cantidad de bacterias con resistencia natural. Con el tiempo, las bacterias resistentes a los antibi\u00f3ticos se multiplican y se propagan.<\/p>\n<p>Para algunas infecciones, los antibi\u00f3ticos eficaces ya no est\u00e1n disponibles. Desarmar las bacterias de las toxinas causantes de enfermedades representa una alternativa prometedora a la disminuci\u00f3n de los antibi\u00f3ticos.<\/p>\n<p><strong>Fuente: xatakaciencia.com<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Seg\u00fan un estudio, publicado en Scientific Reports, las infecciones en humanos podr\u00edan curarse de la misma manera en que se han logrado curar en ratones: sin usar antibi\u00f3ticos.<\/p>\n","protected":false},"author":1,"featured_media":12275,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[370],"tags":[],"class_list":["post-12274","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-salud"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Investigadores curan infecciones resistentes a los medicamentos sin antibi\u00f3ticos - 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