{"id":21947,"date":"2021-03-22T13:17:00","date_gmt":"2021-03-22T19:17:00","guid":{"rendered":"https:\/\/otech.uaeh.edu.mx\/noti\/?p=21947"},"modified":"2021-03-22T13:17:30","modified_gmt":"2021-03-22T19:17:30","slug":"mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral","status":"publish","type":"post","link":"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral\/","title":{"rendered":"Mini-cerebros 3D nos acercan a la regeneraci\u00f3n cerebral"},"content":{"rendered":"

Cient\u00edficos de la Universidad Northwestern, la Universidad de Illinois en Chicago y el Shirley Ryan AbilityLab han creado una tecnolog\u00eda que podr\u00eda acercarnos al sue\u00f1o de la regeneraci\u00f3n cerebral. <\/span><\/span><\/span>Combina cultivos neuronales humanos con sistemas bioelectr\u00f3nicos tridimensionales para crear mini-cerebros, en un enfoque que con una futura incorporaci\u00f3n de c\u00e9lulas madre humanas podr\u00eda desarrollar alternativas para \u00abreparar\u00bb por completo un cerebro da\u00f1ado.<\/span><\/span><\/span><\/span><\/p>\n

De acuerdo a un\u00a0 <\/span><\/span><\/span><\/span>comunicado <\/span><\/span><\/span><\/span>, los cient\u00edficos crearon un peque\u00f1o laboratorio en un plato (placa de Petri), aprovechando un novedoso sistema de interfaz neuronal 3D. <\/span><\/span><\/span>All\u00ed lograron registrar diferentes reacciones en \u00abmini-cerebros\u00bb, creados a partir de cultivos cerebrales.<\/span><\/span><\/span><\/span><\/p>\n

Por ejemplo, introdujeron genes para controlar la actividad neuronal y monitorearla mediante luz. <\/span><\/span><\/span>Los especialistas destacaron que este sistema es capaz de producir diminutos esferoides cerebrales a partir de muestras de c\u00e9lulas humanas, que mantienen la identidad gen\u00e9tica de la persona.<\/span><\/span><\/span><\/span><\/p>\n

La nueva tecnolog\u00eda permitir\u00e1 estudiar caracter\u00edsticas del cerebro humano sin necesidad de involucrar a personas o llevar adelante m\u00e9todos invasivos. <\/span><\/span><\/span>A futuro, los investigadores sostienen que incorporar cultivos cerebrales derivados de c\u00e9lulas madre humanas ser\u00e1 posible realizar intervenciones r\u00e1pidas y eficientes que pr\u00e1cticamente \u00abreparar\u00bb el cerebro por completo.<\/span><\/span><\/span><\/span><\/p>\n

Una nueva frontera<\/span><\/span><\/span><\/span><\/h2>\n

Teniendo en cuenta que actualmente los cultivos de tejidos se combinan con matrices de electrodos en dos dimensiones y planas, que no coinciden con los complejos dise\u00f1os estructurales que se encuentran en el cerebro humano, la nueva tecnolog\u00eda permite un trascendente avance en el estudio de diferentes aspectos cerebrales.<\/span><\/span><\/span><\/span><\/p>\n

Seg\u00fan el Dr. Colin Franz, uno de los autores principales del estudio publicado en la revista Science Advances, \u00ablos avances concretados en esta investigaci\u00f3n marcar\u00e1n una nueva frontera en la forma en que estudiamos y entendemos el cerebro. <\/span><\/span><\/span>Ahora que la plataforma 3D ha sido desarrollada y validada, podremos realizar estudios m\u00e1s espec\u00edficos en nuestros pacientes que se recuperan de una lesi\u00f3n neurol\u00f3gica o luchan contra una enfermedad neurodegenerativa \u00bb, descrito.<\/span><\/span><\/span><\/span><\/p>\n

Los cient\u00edficos creen que su estudio marca solamente el comienzo de una nueva generaci\u00f3n de sistemas bioelectr\u00f3nicos 3D miniaturizados, como en el caso de estos\u00a0 <\/span><\/span><\/span><\/span>mini-cerebros <\/span><\/span><\/span><\/span>, que podr\u00edan expandir de forma casi ilimitada las posibilidades de la medicina regenerativa. <\/span><\/span><\/span>\u00bfEstaremos m\u00e1s cerca de poder regenerar casi al 100% el cerebro y otras partes del cuerpo humano?<\/span><\/span><\/span><\/span><\/p>\n

Aplicaciones sin l\u00edmites<\/span><\/span><\/span><\/span><\/h2>\n

Para Yoonseok Park, otro de los l\u00edderes de la investigaci\u00f3n, las aplicaciones de estas nuevas tecnolog\u00edas incluir\u00e1n \u00abuna serie de dispositivos actualmente en desarrollo que contribuir\u00e1n a la formaci\u00f3n de circuitos neuronales a\u00fan m\u00e1s complejos desde el cerebro hacia los m\u00fasculos, como as\u00ed tambi\u00e9n tejidos cada vez m\u00e1s din\u00e1micos, incluyendo un coraz\u00f3n que late \u00bb, indica.<\/span><\/span><\/span><\/span><\/p>\n

Un dato llamativo remarcado por los investigadores es que los nuevos dispositivos fueron creados a partir de tecnolog\u00eda similar a la que se encuentra en tel\u00e9fonos m\u00f3viles inteligentes y ordenadores, dejando en claro que los componentes son relativamente accesibles.<\/span><\/span><\/span><\/span><\/p>\n

Ahora, estos dispositivos que imitan las complejas formas biol\u00f3gicas que se encuentran en el cerebro humano ser\u00e1n empleados para comprender mejor las enfermedades neurol\u00f3gicas, probar medicamentos y terapias que tienen potencial cl\u00ednico e entender en profundidad las diferencias individuales que marcan la amplia diversidad de resultados observados en la rehabilitaci\u00f3n neurol\u00f3gica.<\/span><\/span><\/span><\/span><\/p>\n

\u00bfExistir\u00e1 un l\u00edmite finalmente para la integraci\u00f3n entre tecnolog\u00eda y biolog\u00eda o el desarrollo de esta simbiosis quedar\u00e1 \u00fanicamente en manos de enfoques \u00e9ticos individuales? <\/span><\/span><\/span>Por lo pronto, todo indica que la innovaci\u00f3n tecnol\u00f3gica parece avanzar m\u00e1s r\u00e1pido que los planteamientos \u00e9ticos, ofreciendo un futuro en el cual el cerebro humano podr\u00eda ser casi eterno.<\/span><\/span><\/span><\/span><\/p>\n

Referencia<\/span><\/span><\/span><\/span><\/h2>\n

Interfaces neuronales tridimensionales y multifuncionales para esferoides corticales y ensambloides dise\u00f1ados<\/span><\/span><\/span><\/span><\/a> . <\/span><\/span><\/span>Parque Yoonseok, Colin Franz et al. <\/span><\/span><\/span>Avances cient\u00edficos (2021). <\/span>DOI: http:\/\/dx.doi.org\/10.1126\/sciadv.abf9153<\/span><\/span><\/span><\/span><\/p>\n

Foto:<\/span><\/span><\/span><\/span><\/strong><\/p>\n

Interfaces neuronales tridimensionales y multifuncionales dise\u00f1adas en el marco de la investigaci\u00f3n. <\/span><\/span><\/span>Cr\u00e9dito: Universidad Northwestern.<\/span><\/span><\/span><\/span><\/strong><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Cient\u00edficos de la Universidad Northwestern, la Universidad de Illinois en Chicago y el Shirley Ryan AbilityLab han creado una tecnolog\u00eda que podr\u00eda acercarnos al sue\u00f1o de la regeneraci\u00f3n cerebral. Combina cultivos neuronales humanos con sistemas bioelectr\u00f3nicos tridimensionales para crear mini-cerebros, en un enfoque que con una futura incorporaci\u00f3n de c\u00e9lulas madre humanas podr\u00eda desarrollar alternativas […]<\/p>\n","protected":false},"author":1,"featured_media":21948,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[370],"tags":[],"class_list":["post-21947","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-salud"],"yoast_head":"\nMini-cerebros 3D nos acercan a la regeneraci\u00f3n cerebral - Observatorio Tecnol\u00f3gico de Hidalgo<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mini-cerebros 3D nos acercan a la regeneraci\u00f3n cerebral - Observatorio Tecnol\u00f3gico de Hidalgo\" \/>\n<meta property=\"og:description\" content=\"Cient\u00edficos de la Universidad Northwestern, la Universidad de Illinois en Chicago y el Shirley Ryan AbilityLab han creado una tecnolog\u00eda que podr\u00eda acercarnos al sue\u00f1o de la regeneraci\u00f3n cerebral. Combina cultivos neuronales humanos con sistemas bioelectr\u00f3nicos tridimensionales para crear mini-cerebros, en un enfoque que con una futura incorporaci\u00f3n de c\u00e9lulas madre humanas podr\u00eda desarrollar alternativas […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral\/\" \/>\n<meta property=\"og:site_name\" content=\"Observatorio Tecnol\u00f3gico de Hidalgo\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/observatoriouaeh\" \/>\n<meta property=\"article:published_time\" content=\"2021-03-22T19:17:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-03-22T19:17:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/otech.uaeh.edu.mx\/noti\/wp-content\/uploads\/2021\/03\/mini-cerebros-3d-regeneracion-cerebral-740x614-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"740\" \/>\n\t<meta property=\"og:image:height\" content=\"614\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@OBSERVATORIOEH\" \/>\n<meta name=\"twitter:site\" content=\"@OBSERVATORIOEH\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral\/\"},\"author\":{\"name\":\"admin\",\"@id\":\"https:\/\/otech.uaeh.edu.mx\/noti\/#\/schema\/person\/95263d004158ffabcd98137e1d0abc1c\"},\"headline\":\"Mini-cerebros 3D nos acercan a la regeneraci\u00f3n cerebral\",\"datePublished\":\"2021-03-22T19:17:00+00:00\",\"dateModified\":\"2021-03-22T19:17:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral\/\"},\"wordCount\":693,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/otech.uaeh.edu.mx\/noti\/#organization\"},\"image\":{\"@id\":\"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/otech.uaeh.edu.mx\/noti\/wp-content\/uploads\/2021\/03\/mini-cerebros-3d-regeneracion-cerebral-740x614-1.jpg\",\"articleSection\":[\"Salud\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral\/\",\"url\":\"https:\/\/otech.uaeh.edu.mx\/noti\/salud\/mini-cerebros-3d-nos-acercan-a-la-regeneracion-cerebral\/\",\"name\":\"Mini-cerebros 3D nos acercan a la regeneraci\u00f3n cerebral - 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